| Gene Information | |
|---|---|
| Gene Name | SUMO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 101 |
| Protein Names | Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000116030 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P63165 |
| Gene Card | SUMO1 |
| Uniprot ID | P63165 |
| Pfam | PF11976 |
| In ASD | no |
| Allosteric Prediction | yes (0.159081586) |
| Ortholog in Animals | Alpaca_ SUMO1 ( ortholog_one2one ) Dog_ SUMO1 ( ortholog_one2one ) GuineaPig_ SUMO1 ( ortholog_one2one ) Mouse_ Sumo1 ( ortholog_one2one ) Rat_ Sumo1 ( ortholog_one2one ) Rabbit_ SUMO1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A5R (NMR - ) 1TGZ (X-ray 2.80A ) 1WYW (X-ray 2.10A ) 1Y8R (X-ray 2.75A ) 1Z5S (X-ray 3.01A ) 2ASQ (NMR - ) 2BF8 (X-ray 2.30A ) 2G4D (X-ray 2.80A ) 2IO2 (X-ray 2.90A ) 2IY0 (X-ray 2.77A ) 2IY1 (X-ray 2.46A ) 2KQS (NMR - ) 2LAS (NMR - ) 2MW5 (NMR - ) 2N1A (NMR - ) 2N1V (NMR - ) 2PE6 (X-ray 2.40A ) 2UYZ (X-ray 1.40A ) 2VRR (X-ray 2.22A ) 3KYC (X-ray 2.45A ) 3KYD (X-ray 2.61A ) 3RZW (X-ray 2.15A ) 3UIP (X-ray 2.29A ) 4WJN (X-ray 1.50A ) 4WJO (X-ray 1.46A ) 4WJP (X-ray 1.70A ) 4WJQ (X-ray 1.35A ) 5AEK (X-ray 3.00A ) 5B7A (NMR - ) 5ELJ (X-ray 1.98A ) 5GHD (NMR - ) 6EOP (X-ray 2.40A ) 6EOT (X-ray 3.50A ) 6J4I (NMR - ) 6JXU (NMR - ) 6JXV (NMR - ) 6K5T (NMR - ) 6TRW (X-ray 3.00A ) 6UYO (X-ray 1.64A ) 6UYP (X-ray 1.42A ) 6UYQ (X-ray 1.50A ) 6UYR (X-ray 1.30A ) 6UYS (X-ray 1.59A ) 6UYT (X-ray 1.66A ) 6UYU (X-ray 1.66A ) 6UYV (X-ray 1.40A ) 6UYX (X-ray 1.70A ) 6UYY (X-ray 1.60A ) 6UYZ (X-ray 1.40A ) 6V7P (X-ray 1.40A ) 6V7Q (X-ray 1.35A ) 6V7R (X-ray 1.55A ) 6V7S (X-ray 1.47A ) 6WW3 (X-ray 2.10A ) 6XOG (X-ray 1.98A ) 6XOH (X-ray 2.23A ) 6XOI (X-ray 2.00A ) 8DJH (X-ray 1.77A ) 8DJI (X-ray 1.97A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus membrane {ECO:0000269|PubMed:10574707, ECO:0000269|PubMed:12383504}. Nucleus speckle {ECO:0000250|UniProtKB:P63166}. Cytoplasm {ECO:0000269|PubMed:12383504, ECO:0000269|PubMed:9162015}. Nucleus, PML body {ECO:0000269|PubMed:10574707, ECO:0000269|PubMed:12383504, ECO:0000269|PubMed:22406621}. Cell membrane {ECO:0000269|PubMed:19223394}. Nucleus {ECO:0000269|PubMed:24651376, ECO:0000269|PubMed:9162015}. Note=Recruited by BCL11A into the nuclear body (By similarity). In the presence of ZFHX3, sequesterd to nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body (PubMed:24651376). {ECO:0000250|UniProtKB:P63166, ECO:0000269|PubMed:24651376}. |
| Mouse PG classification | NA |
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