| Gene Information | |
|---|---|
| Gene Name | SUMF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 301 |
| Protein Names | Inactive C-alpha-formylglycine-generating enzyme 2 (Paralog of formylglycine-generating enzyme) (pFGE) (Sulfatase-modifying factor 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 12 ( ENSG00000129103 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8NBJ7 |
| Gene Card | SUMF2 |
| Uniprot ID | Q8NBJ7 |
| Pfam | PF03781 |
| In ASD | no |
| Allosteric Prediction | no (-0.755817055) |
| Ortholog in Animals | Dog_ SUMF2 ( ortholog_one2one ) GuineaPig_ SUMF2 ( ortholog_one2one ) Mouse_ Sumf2 ( ortholog_one2one ) Pig_ SUMF2 ( ortholog_one2one ) Rat_ Sumf2 ( ortholog_one2one ) Rabbit_ SUMF2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SUMF1 |
| Tissue | NA |
| Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta. {ECO:0000269|PubMed:15708861, ECO:0000269|PubMed:15962010}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Y4J (X-ray 1.86A ) |
| DBSNP | rs4245575 rs778487055 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000269|PubMed:15708861, ECO:0000269|PubMed:15962010, ECO:0000269|PubMed:18266766}. |
| Mouse PG classification | NA |
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