| Gene Information | |
|---|---|
| Gene Name | SULT4A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 284 |
| Protein Names | Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000130540 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BR01 |
| Gene Card | SULT4A1 |
| Uniprot ID | Q9BR01 |
| Pfam | PF00685 |
| In ASD | no |
| Allosteric Prediction | no (-0.251448563) |
| Ortholog in Animals | Alpaca_ SULT4A1 ( ortholog_one2one ) Dog_ SULT4A1 ( ortholog_one2one ) GuineaPig_ SULT4A1 ( ortholog_one2one ) Macaque_ SULT4A1 ( ortholog_one2one ) Mouse_ Sult4a1 ( ortholog_one2one ) Pig_ SULT4A1 ( ortholog_one2one ) Rat_ Sult4a1 ( ortholog_one2one ) Rabbit_ SULT4A1 ( ortholog_one2one ) |
| Ohnologs | SULT2B1, SULT2A1, SULT1E1, SULT1B1, SULT1C3, SULT1C2, SLX1A-SULT1A3, SULT1A4 |
| Paralogs | SULT1C2, SULT2B1, SULT1B1, SULT1C3, SULT6B1, SULT1C4, SULT2A1, SULT1A2, SULT1A1, SULT1A4, SULT1A3, SULT1E1 |
| Tissue | brain, cerebral.cortex, small.intestine, spleen, testis |
| Tissue Specificity | Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum, occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No expression detected in the pancreas (PubMed:10698717). Highly expressed in fetal brain and occipital lobe, slightly less in the whole brain, frontal lobe, hippocampus, and lung, very low expression in cerebellum, medulla oblongata, temporal lobe, testis, kidney and appendix (PubMed:12039030). {ECO:0000269|PubMed:10698717, ECO:0000269|PubMed:12039030}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1ZD1 (X-ray 2.24A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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