| Gene Information | |
|---|---|
| Gene Name | MATE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 570 |
| Protein Names | Multidrug and toxin extrusion protein 1 (MATE-1) (hMATE-1) (Solute carrier family 47 member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96FL8 |
| Gene Card | SLC47A1 |
| Uniprot ID | Q96FL8 |
| Pfam | PF01554 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. The highest expression is found in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney. {ECO:0000269|PubMed:16330770, ECO:0000269|PubMed:17509534}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35790011 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16641166, ECO:0000269|PubMed:18305230, ECO:0000269|PubMed:19158817}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:16330770}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the plasma membrane; at the brush border membranes of the proximal tubules (kidney) and at the bile caniculi (liver). {ECO:0000269|PubMed:16330770}. |
| Mouse PG classification | NA |
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