| Gene Information | |
|---|---|
| Gene Name | SUA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 346 |
| Protein Names | SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A) [Cleaved into: SUMO-activating enzyme subunit 1, N-terminally processed] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UBE0 |
| Gene Card | SAE1 |
| Uniprot ID | Q9UBE0 |
| Pfam | PF00899 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expression level increases during S phase and drops in G2 phase (at protein level). {ECO:0000269|PubMed:11481243}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001704(Rat);0.061538(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Y8Q (X-ray 2.25A ) 1Y8R (X-ray 2.75A ) 3KYC (X-ray 2.45A ) 3KYD (X-ray 2.61A ) 6CWY (X-ray 2.46A ) 6CWZ (X-ray 3.10A ) 6XOG (X-ray 1.98A ) 6XOH (X-ray 2.23A ) 6XOI (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11481243}. |
| Mouse PG classification | NA |
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