Gene Information
Gene NameSTYXL2
OrganismHomo sapiens (Human)
Gene Length1158
Protein NamesSerine/threonine/tyrosine-interacting-like protein 2 (Inactive dual specificity phosphatase 27)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000198842 )
Evolutionary StageVertebrata
AlphaFoldDBQ5VZP5
Gene CardSTYXL2
Uniprot IDQ5VZP5
PfamPF00782
In ASDno
Allosteric Predictionno (-0.328633009)
Ortholog in AnimalsAlpaca_ STYXL2 ( ortholog_one2one )
Dog_ STYXL2 ( ortholog_one2one )
GuineaPig_ STYXL2 ( ortholog_one2one )
Macaque_ STYXL2 ( ortholog_one2one )
Mouse_ Dusp27 ( ortholog_one2one )
Pig_ STYXL2 ( ortholog_one2one )
Rat_ Dusp27 ( ortholog_one2one )
Rabbit_ STYXL2 ( ortholog_one2one )
OhnologsNA
ParalogsDUSP6, DUSP4, DUSP12, DUSP10, SSH3, DUSP19, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP7, DUSP26, STYX, SSH2, PTPMT1, DUSP22, DUSP18, DUSP15, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9, DUSP3
Tissueheart, skeletal.muscle, artery, left.atrium, left.ventricle, mitral.valve, penis, pulmonary.valve, tongue, atrium
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs267745  rs6668826  rs3795605  rs267746  rs2281959 
Subcellular location [CC]Cytoplasm, myofibril, sarcomere {ECO:0000250|UniProtKB:F1QWM2}.
Mouse PG classificationNA
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