Gene Information
Gene NameSTYX
OrganismHomo sapiens (Human)
Gene Length223
Protein NamesSerine/threonine/tyrosine-interacting protein (Inactive tyrosine-protein phosphatase STYX) (Phosphoserine/threonine/tyrosine interaction protein)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000198252 )
Evolutionary StageEukaryota
AlphaFoldDBQ8WUJ0
Gene CardSTYX
Uniprot IDQ8WUJ0
PfamPF00782
In ASDno
Allosteric Predictionno (-0.869862146)
Ortholog in AnimalsAlpaca_ STYX ( ortholog_one2one )
Dog_ STYX ( ortholog_one2one )
GuineaPig_ STYX ( ortholog_one2one )
Macaque_ STYX ( ortholog_one2one )
Mouse_ Styx ( ortholog_one2many )
Mouse_ Styx-ps ( ortholog_one2many )
Pig_ STYX ( ortholog_one2one )
Rat_ Styx ( ortholog_one2one )
Rabbit_ STYX ( ortholog_one2one )
OhnologsNA
ParalogsDUSP6, DUSP4, DUSP12, DUSP10, STYXL2, SSH3, DUSP19, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP7, DUSP26, SSH2, PTPMT1, DUSP22, DUSP18, DUSP15, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9, DUSP3
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2R0B  (X-ray  1.60A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:23847209, ECO:0000269|PubMed:28007894}. Cytoplasm, cytosol {ECO:0000269|PubMed:23847209}. Note=Predominantly localizes to the nucleus. {ECO:0000269|PubMed:23847209, ECO:0000269|PubMed:28007894}.
Mouse PG classificationNA
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