| Gene Information | |
|---|---|
| Gene Name | STX8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 236 |
| Protein Names | Syntaxin-8 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000170310 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UNK0 |
| Gene Card | STX8 |
| Uniprot ID | Q9UNK0 |
| Pfam | PF05739 |
| In ASD | no |
| Allosteric Prediction | no (-1.114899425) |
| Ortholog in Animals | Alpaca_ STX8 ( ortholog_one2one ) Dog_ STX8 ( ortholog_one2one ) GuineaPig_ STX8 ( ortholog_one2one ) Macaque_ STX8 ( ortholog_one2one ) Mouse_ Stx8 ( ortholog_one2one ) Pig_ STX8 ( ortholog_one2one ) Rat_ Stx8 ( ortholog_one2one ) Rabbit_ STX8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | STX10, STX6 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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