| Gene Information | |
|---|---|
| Gene Name | CFAP58 |
| Organism | Homo sapiens (Human) |
| Gene Length | 872 |
| Protein Names | Cilia- and flagella-associated protein 58 (Coiled-coil domain-containing protein 147) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000120051 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5T655 |
| Gene Card | CFAP58 |
| Uniprot ID | Q5T655 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.777065505) |
| Ortholog in Animals | Alpaca_ CFAP58 ( ortholog_one2one ) GuineaPig_ CFAP58 ( ortholog_one2one ) Macaque_ CFAP58 ( ortholog_one2one ) Mouse_ Cfap58 ( ortholog_one2one ) Pig_ CFAP58 ( ortholog_one2one ) Rat_ Cfap58 ( ortholog_one2one ) Rabbit_ CFAP58 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CCDC146 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11192036 rs7087328 |
| Subcellular location [CC] | Cell projection, cilium {ECO:0000250|UniProtKB:A8HUA1}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:32791035, ECO:0000269|PubMed:33314088}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:B2RW38}. Note=Localized to the entire flagellum and predominantly concentrated in the midpiece. Co-localizes with ODFP2 at the centrosome (By similarity). {ECO:0000250|UniProtKB:B2RW38, ECO:0000269|PubMed:32791035}. |
| Mouse PG classification | NA |
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