| Gene Information | |
|---|---|
| Gene Name | STX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | Syntaxin-1A (Neuron-specific antigen HPC-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q16623 |
| Gene Card | STX1A |
| Uniprot ID | Q16623 |
| Pfam | PF05739; PF00804 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Highly expressed in embryonic spinal cord and ganglia and in adult cerebellum and cerebral cortex. {ECO:0000269|PubMed:10644452}.; [Isoform 2]: Expressed in heart, liver, fat, skeletal muscle, kidney and brain. {ECO:0000269|PubMed:10644452}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.027881(Rat);0.043560(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:O35526}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:O35526}. Synapse, synaptosome {ECO:0000250|UniProtKB:O35526}. Cell membrane {ECO:0000250|UniProtKB:P32851}. Note=Colocalizes with KCNB1 at the cell membrane. {ECO:0000250|UniProtKB:P32851}.; [Isoform 2]: Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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