| Gene Information | |
|---|---|
| Gene Name | ACADVL |
| Organism | Homo sapiens (Human) |
| Gene Length | 655 |
| Protein Names | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000072778 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P49748 |
| Gene Card | ACADVL |
| Uniprot ID | P49748 |
| Pfam | PF00441; PF02770; PF02771 |
| In ASD | no |
| Allosteric Prediction | no (-0.258797532) |
| Ortholog in Animals | Alpaca_ ACADVL ( ortholog_one2one ) Dog_ ACADVL ( ortholog_one2one ) GuineaPig_ ACADVL ( ortholog_one2one ) Macaque_ ACADVL ( ortholog_one2one ) Mouse_ Acadvl ( ortholog_one2one ) Pig_ ACADVL ( ortholog_one2one ) Rat_ Acadvl ( ortholog_one2one ) Rabbit_ ACADVL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACOX1, ACAD11, ACADM, ACAD9, IVD, GCDH, ACOXL, ACAD10, ACADS, ACOX3, ACAD8, ACOX2, ACADSB, ACADL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001823(Rat);0.016667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2UXW (X-ray 1.45A ) 3B96 (X-ray 1.91A ) |
| DBSNP | rs2230179 rs2230178 rs28934585 rs387906251 rs746688190 rs369560930 rs545215807 rs140629318 rs1432183079 rs387906253 rs113994168 rs113994167 rs866464446 rs200573371 rs774716484 rs398123095 rs1051701 rs771874163 rs112406105 rs1057517281 rs118204015 rs2309689 rs118204016 rs138058572 rs1419606204 rs794727112 rs118204017 rs766742117 rs200366828 rs398123083 rs113994170 rs759775666 rs2230180 rs1085307648 rs118204014 rs148584617 rs13383 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:9461620, ECO:0000269|PubMed:9599005}; Peripheral membrane protein {ECO:0000269|PubMed:9599005}.; [Isoform 2]: Mitochondrion inner membrane {ECO:0000269|PubMed:17374501}; Peripheral membrane protein {ECO:0000269|PubMed:17374501}. |
| Mouse PG classification | HPG |
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