| Gene Information | |
|---|---|
| Gene Name | STRA6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 667 |
| Protein Names | Receptor for retinol uptake STRA6 (Retinol-binding protein receptor STRA6) (Stimulated by retinoic acid gene 6 protein homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000137868 ) 3 ( ENSG00000288257 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9BX79 |
| Gene Card | STRA6 |
| Uniprot ID | Q9BX79 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.292260921) |
| Ortholog in Animals | Alpaca_ STRA6 ( ortholog_one2one ) Dog_ STRA6 ( ortholog_one2one ) GuineaPig_ STRA6 ( ortholog_one2one ) Macaque_ STRA6 ( ortholog_one2one ) Mouse_ Stra6 ( ortholog_one2one ) Pig_ STRA6 ( ortholog_one2one ) Rat_ Stra6 ( ortholog_one2one ) Rabbit_ STRA6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CCDC180 |
| Tissue | NA |
| Tissue Specificity | Broad expression. In adult eye expressed in sclera, retina, retinal pigment epithelium, and trabecular meshwork but not in choroid and iris. {ECO:0000269|PubMed:17273977}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs118203961 rs909629751 rs118203958 rs151341424 rs118203962 rs17852249 rs869025269 rs11545567 rs736118 rs144691445 rs118203960 rs118203959 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18316031, ECO:0000269|PubMed:21901792, ECO:0000269|PubMed:9452451}; Multi-pass membrane protein {ECO:0000305}. Note=In the retinal pigment epithelium localizes to the basolateral membrane. {ECO:0000250|UniProtKB:Q0V8E7}. |
| Mouse PG classification | LPG |
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