| Gene Information | |
|---|---|
| Gene Name | TSEN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 465 |
| Protein Names | tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000154743 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NCE0 |
| Gene Card | TSEN2 |
| Uniprot ID | Q8NCE0 |
| Pfam | PF01974; PF02778 |
| In ASD | no |
| Allosteric Prediction | no (-1.089508047) |
| Ortholog in Animals | Alpaca_ TSEN2 ( ortholog_one2one ) Dog_ TSEN2 ( ortholog_one2one ) Macaque_ TSEN2 ( ortholog_one2one ) Mouse_ Tsen2 ( ortholog_one2one ) Pig_ TSEN2 ( ortholog_one2one ) Rat_ Tsen2 ( ortholog_one2one ) Rabbit_ TSEN2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 and isoform 2 are widely expressed at very low level. {ECO:0000269|PubMed:15109492}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12495784 rs33955793 rs113994149 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15109492}. Nucleus, nucleolus {ECO:0000269|PubMed:15109492}. Note=May be transiently localized in the nucleolus. |
| Mouse PG classification | NA |
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