| Gene Information | |
|---|---|
| Gene Name | REEP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 252 |
| Protein Names | Receptor expression-enhancing protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000132563 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BRK0 |
| Gene Card | REEP2 |
| Uniprot ID | Q9BRK0 |
| Pfam | PF03134 |
| In ASD | no |
| Allosteric Prediction | no (-1.415769742) |
| Ortholog in Animals | Alpaca_ REEP2 ( ortholog_one2one ) Dog_ REEP2 ( ortholog_one2one ) GuineaPig_ REEP2 ( ortholog_one2one ) Macaque_ REEP2 ( ortholog_one2one ) Mouse_ Reep2 ( ortholog_one2one ) Pig_ REEP2 ( ortholog_one2one ) Rat_ Reep2 ( ortholog_one2one ) Rabbit_ REEP2 ( ortholog_one2one ) |
| Ohnologs | REEP3, REEP4, REEP1 |
| Paralogs | REEP3, REEP5, REEP6, REEP1, REEP4 |
| Tissue | cerebral.cortex, brain |
| Tissue Specificity | Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas (PubMed:11161817). Expressed in circumvallate papillae (PubMed:16720576). {ECO:0000269|PubMed:11161817, ECO:0000269|PubMed:16720576}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs483352923 rs483352925 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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