| Gene Information | |
|---|---|
| Gene Name | STOT |
| Organism | Homo sapiens (Human) |
| Gene Length | 601 |
| Protein Names | Cdc42-interacting protein 4 (Protein Felic) (Salt tolerant protein) (hSTP) (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15642 |
| Gene Card | TRIP10 |
| Uniprot ID | Q15642 |
| Pfam | PF00611; PF00018 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea. {ECO:0000269|PubMed:11294612, ECO:0000269|PubMed:12054674, ECO:0000269|PubMed:12456510, ECO:0000269|PubMed:12604778, ECO:0000269|PubMed:9210375}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CT4 (NMR - ) 2EFK (X-ray 2.30A ) 2KE4 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup. Note=Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity). Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9. {ECO:0000250}.; [Isoform 5]: Cytoplasm, perinuclear region. |
| Mouse PG classification | NA |
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