| Gene Information | |
|---|---|
| Gene Name | STMN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 179 |
| Protein Names | Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000104435 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q93045 |
| Gene Card | STMN2 |
| Uniprot ID | Q93045 |
| Pfam | PF00836 |
| In ASD | no |
| Allosteric Prediction | no (-0.549811696) |
| Ortholog in Animals | Alpaca_ STMN2 ( ortholog_one2one ) Dog_ STMN2 ( ortholog_one2one ) Macaque_ STMN2 ( ortholog_one2one ) Mouse_ Stmn2 ( ortholog_one2one ) Pig_ STMN2 ( ortholog_one2one ) Rat_ Stmn2 ( ortholog_one2one ) Rabbit_ STMN2 ( ortholog_one2one ) |
| Ohnologs | STMN4, STMN1 |
| Paralogs | STMN3, STMND1, STMN4, STMN1 |
| Tissue | cerebral.cortex, brain |
| Tissue Specificity | Neuron specific. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, growth cone. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, axon. Golgi apparatus. Endosome {ECO:0000250}. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia. {ECO:0000250}. |
| Mouse PG classification | NA |
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