| Gene Information | |
|---|---|
| Gene Name | POLG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 485 |
| Protein Names | DNA polymerase subunit gamma-2, mitochondrial (DNA polymerase gamma accessory 55 kDa subunit) (p55) (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000256525 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UHN1 |
| Gene Card | POLG2 |
| Uniprot ID | Q9UHN1 |
| Pfam | PF03129 |
| In ASD | no |
| Allosteric Prediction | no (-0.983684201) |
| Ortholog in Animals | Alpaca_ POLG2 ( ortholog_one2one ) Dog_ POLG2 ( ortholog_one2one ) GuineaPig_ POLG2 ( ortholog_one2one ) Macaque_ POLG2 ( ortholog_one2one ) Mouse_ Polg2 ( ortholog_one2one ) Pig_ POLG2 ( ortholog_one2one ) Rat_ Polg2 ( ortholog_one2one ) Rabbit_ POLG2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GARS1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2G4C (X-ray 3.15A ) 3IKL (X-ray 3.10A ) 3IKM (X-ray 3.24A ) 4ZTU (X-ray 3.30A ) 4ZTZ (X-ray 3.44A ) 5C51 (X-ray 3.43A ) 5C52 (X-ray 3.64A ) 5C53 (X-ray 3.57A ) |
| DBSNP | rs1427463 rs886037843 rs17850455 rs104894632 |
| Subcellular location [CC] | Mitochondrion. |
| Mouse PG classification | LPG |
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