| Gene Information | |
|---|---|
| Gene Name | STK40 |
| Organism | Homo sapiens (Human) |
| Gene Length | 435 |
| Protein Names | Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000196182 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N2I9 |
| Gene Card | STK40 |
| Uniprot ID | Q8N2I9 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.589408835) |
| Ortholog in Animals | Alpaca_ STK40 ( ortholog_one2one ) Dog_ STK40 ( ortholog_one2one ) GuineaPig_ STK40 ( ortholog_one2one ) Macaque_ STK40 ( ortholog_one2one ) Mouse_ Stk40 ( ortholog_one2one ) Pig_ STK40 ( ortholog_one2one ) Rat_ Stk40 ( ortholog_one2one ) Rabbit_ STK40 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TRIB2, TRIB3, TRIB1 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in heart, brain, placenta, lung, skeletal muscle, kidney, spleen, thymus, prostate, liver, pancreas, testis, ovary, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:13679039}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004067(Rat);0.076923(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5L2Q (X-ray 2.53A ) |
| DBSNP | rs56314546 rs755089893 rs539738963 rs3795498 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:13679039}. Cytoplasm {ECO:0000269|PubMed:13679039}. |
| Mouse PG classification | NA |
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