| Gene Information | |
|---|---|
| Gene Name | TREX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 236 |
| Protein Names | Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 25 ( ENSG00000183479 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BQ50 |
| Gene Card | TREX2 |
| Uniprot ID | Q9BQ50 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.133021162) |
| Ortholog in Animals | GuineaPig_ TREX2 ( ortholog_one2one ) Mouse_ Trex2 ( ortholog_one2one ) Rat_ Trex2 ( ortholog_one2one ) Rabbit_ TREX2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TREX1 |
| Tissue | NA |
| Tissue Specificity | Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus. {ECO:0000269|PubMed:11278605}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Y97 (X-ray 2.50A ) |
| DBSNP | rs35132777 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |