| Gene Information | |
|---|---|
| Gene Name | STK35 |
| Organism | Homo sapiens (Human) |
| Gene Length | 534 |
| Protein Names | Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1) |
| Target Name | serine/threonine-protein kinase 35 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000125834 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TDR2 |
| Gene Card | STK35 |
| Uniprot ID | Q8TDR2 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.905667793) |
| Ortholog in Animals | Alpaca_ STK35 ( ortholog_one2one ) GuineaPig_ STK35 ( ortholog_one2one ) Macaque_ STK35 ( ortholog_one2one ) Mouse_ Stk35 ( ortholog_one2one ) Pig_ STK35 ( ortholog_one2one ) Rat_ Stk35 ( ortholog_one2one ) Rabbit_ STK35 ( ortholog_one2one ) |
| Ohnologs | PDIK1L |
| Paralogs | PKMYT1, EIF2AK3, EIF2AK4, WEE2, EIF2AK2, WEE1, PDIK1L, EIF2AK1 |
| Tissue | NA |
| Tissue Specificity | Expressed in testis. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found in cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in the nucleus, and the presence of PDLIM1 had no influence on its location. {ECO:0000269|PubMed:11973348}. |
| Mouse PG classification | NA |
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