Gene Information
Gene NameSTK33
OrganismHomo sapiens (Human)
Gene Length514
Protein NamesSerine/threonine-protein kinase 33 (EC 2.7.11.1)
Target Nameserine/threonine-protein kinase 33
Target TypeNA
Gene Age>4290 ( ENSG00000130413 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9BYT3
Gene CardSTK33
Uniprot IDQ9BYT3
PfamPF00069
In ASDno
Allosteric Predictionyes (0.297967762)
Ortholog in AnimalsAlpaca_ STK33 ( ortholog_one2one )
Dog_ STK33 ( ortholog_one2one )
GuineaPig_ STK33 ( ortholog_one2one )
Macaque_ STK33 ( ortholog_one2one )
Mouse_ Stk33 ( ortholog_one2one )
Pig_ STK33 ( ortholog_one2one )
Rat_ Stk33 ( ortholog_one2one )
Rabbit_ STK33 ( ortholog_one2one )
OhnologsNA
ParalogsDCLK3, PHKG1, MYLK4, CAMKK1, CAMKK2, DCLK2, PSKH1, PNCK, CAMK1D, CAMKV, CAMK2B, CAMK1, STK11, PHKG2, DCLK1, PSKH2, CAMK2G, MYLK2, CAMK2D, CAMK2A, MYLK3, CAMK1G
Tissueoviduct, testis
Tissue SpecificityHighly expressed in testis, fetal lung and heart, followed by pituitary gland, kidney, interventricular septum, pancreas, heart, trachea, thyroid gland and uterus. Weak hybridization signals were observed in the following tissues: amygdala, aorta, esophagus, colon ascending, colon transverse, skeletal muscle, spleen, peripheral blood leukocyte, lymph node, bone marrow, placenta, prostate, liver, salivary gland, mammary gland, some tumor cell lines, fetal brain, fetal liver, fetal spleen and fetal thymus. No signal at all was detectable in RNA from tissues of the nervous system. {ECO:0000269|PubMed:11738831, ECO:0000269|PubMed:16176263}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs60786172  rs34525052  rs3751096  rs3751095  rs35296353 
Subcellular location [CC]Cytoplasm, perinuclear region {ECO:0000250}.
Mouse PG classificationNA
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