| Gene Information | |
|---|---|
| Gene Name | AGXT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 514 |
| Protein Names | Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT) |
| Target Name | alanine--glyoxylate aminotransferase 2, mitochondrial |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000113492 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BYV1 |
| Gene Card | AGXT2 |
| Uniprot ID | Q9BYV1 |
| Pfam | PF00202 |
| In ASD | no |
| Allosteric Prediction | yes (0.451729848) |
| Ortholog in Animals | Alpaca_ AGXT2 ( ortholog_one2one ) Dog_ AGXT2 ( ortholog_one2one ) GuineaPig_ AGXT2 ( ortholog_one2one ) Macaque_ AGXT2 ( ortholog_one2one ) Mouse_ Agxt2 ( ortholog_one2one ) Pig_ AGXT2 ( ortholog_one2one ) Rat_ Agxt2 ( ortholog_one2one ) Rabbit_ AGXT2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PHYKPL, OAT, ABAT, ETNPPL |
| Tissue | kidney, liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.157009(Rat);0.082927(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs37370 rs37370 rs37370 rs16870794 rs37369 rs180749 rs17245714 rs16899974 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:20018850, ECO:0000269|PubMed:24586340}. |
| Mouse PG classification | NA |
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