| Gene Information | |
|---|---|
| Gene Name | RGS17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 210 |
| Protein Names | Regulator of G-protein signaling 17 (RGS17) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000091844 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UGC6 |
| Gene Card | RGS17 |
| Uniprot ID | Q9UGC6 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-0.596483198) |
| Ortholog in Animals | Alpaca_ RGS17 ( ortholog_one2one ) Dog_ RGS17 ( ortholog_one2one ) GuineaPig_ RGS17 ( ortholog_one2one ) Macaque_ RGS17 ( ortholog_one2one ) Mouse_ Rgs17 ( ortholog_one2one ) Pig_ RGS17 ( ortholog_one2one ) Rat_ Rgs17 ( ortholog_one2one ) Rabbit_ RGS17 ( ortholog_one2one ) |
| Ohnologs | RGS20, RGS19 |
| Paralogs | RGS18, RGS5, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS7, RGS14, AXIN2, RGS22, RGS4, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in the cerebellum. Also expressed in the cortex and medulla. Weakly expressed in a number of peripheral tissues notably spleen, lung and leukocytes. {ECO:0000269|PubMed:15096504}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1ZV4 (X-ray 2.40A ) 6AM3 (X-ray 1.53A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:Q9QZB0}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q9QZB0}. Nucleus {ECO:0000250|UniProtKB:Q9QZB0}. Cytoplasm {ECO:0000250|UniProtKB:Q9QZB0}. |
| Mouse PG classification | NA |
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