| Gene Information | |
|---|---|
| Gene Name | STK17B |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2) |
| Target Name | serine/threonine-protein kinase 17b |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000081320 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O94768 |
| Gene Card | STK17B |
| Uniprot ID | O94768 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.096084824) |
| Ortholog in Animals | Alpaca_ STK17B ( ortholog_one2one ) Dog_ STK17B ( ortholog_one2one ) GuineaPig_ STK17B ( ortholog_one2one ) Macaque_ STK17B ( ortholog_one2one ) Mouse_ Stk17b ( ortholog_one2one ) Pig_ STK17B ( ortholog_one2one ) Rat_ Stk17b ( ortholog_one2one ) Rabbit_ STK17B ( ortholog_one2one ) |
| Ohnologs | STK17A |
| Paralogs | STK17A |
| Tissue | NA |
| Tissue Specificity | Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:9786912}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LM0 (X-ray 2.35A ) 3LM5 (X-ray 2.29A ) 6QF4 (X-ray 2.50A ) 6Y6F (X-ray 1.98A ) 6Y6H (X-ray 1.95A ) 6ZJF (X-ray 1.75A ) 7AKG (X-ray 2.08A ) |
| DBSNP | rs34740616 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9786912}. Cell membrane {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250}. Note=Colocalizes with STK17B at the plasma membrane. {ECO:0000250}. |
| Mouse PG classification | NA |
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