| Gene Information | |
|---|---|
| Gene Name | GPR85 |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164604 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P60893 |
| Gene Card | GPR85 |
| Uniprot ID | P60893 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-1.08869234) |
| Ortholog in Animals | Alpaca_ GPR85 ( ortholog_one2one ) Dog_ GPR85 ( ortholog_one2one ) GuineaPig_ GPR85 ( ortholog_one2one ) Macaque_ GPR85 ( ortholog_one2one ) Mouse_ Gpr85 ( ortholog_one2one ) Pig_ GPR85 ( ortholog_one2one ) Rat_ Gpr85 ( ortholog_one2one ) Rabbit_ GPR85 ( ortholog_one2one ) |
| Ohnologs | GPR173, GPR27 |
| Paralogs | GPR173, GPR27 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and spinal cord. {ECO:0000269|PubMed:10833454, ECO:0000269|PubMed:10978537}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:25780553}. |
| Mouse PG classification | NA |
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