| Gene Information | |
|---|---|
| Gene Name | STAU1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 577 |
| Protein Names | Double-stranded RNA-binding protein Staufen homolog 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000124214 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95793 |
| Gene Card | STAU1 |
| Uniprot ID | O95793 |
| Pfam | PF00035; PF16482 |
| In ASD | no |
| Allosteric Prediction | no (-0.070233053) |
| Ortholog in Animals | Alpaca_ STAU1 ( ortholog_one2one ) Dog_ STAU1 ( ortholog_one2one ) GuineaPig_ STAU1 ( ortholog_one2one ) Macaque_ STAU1 ( ortholog_one2one ) Mouse_ Stau1 ( ortholog_one2one ) Pig_ STAU1 ( ortholog_one2one ) Rat_ Stau1 ( ortholog_one2one ) Rabbit_ STAU1 ( ortholog_one2one ) |
| Ohnologs | STAU2 |
| Paralogs | TARBP2, ADAT1, ADARB2, PRKRA, ILF3, STRBP, ZFR, ADAD1, ADARB1, STAU2, ILF2, ZFR2, ADAR, ADAD2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.004768(Mouse);0.001123(Rat);0.009779(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DKK (X-ray 1.70A ) 6HTU (X-ray 2.89A ) 6SDW (NMR - ) 6SDY (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19029303}. Rough endoplasmic reticulum {ECO:0000269|PubMed:19029303}. Note=Localizes exclusively with the rough reticulum endoplasmic (RER). |
| Mouse PG classification | NA |
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