| Gene Information | |
|---|---|
| Gene Name | STAT5B |
| Organism | Homo sapiens (Human) |
| Gene Length | 787 |
| Protein Names | Signal transducer and activator of transcription 5B |
| Target Name | signal transducer and activator of transcription 5b |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000173757 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P51692 |
| Gene Card | STAT5B |
| Uniprot ID | P51692 |
| Pfam | PF00017; PF01017; PF02864; PF02865 |
| In ASD | no |
| Allosteric Prediction | yes (0.842546364) |
| Ortholog in Animals | Alpaca_ STAT5B ( ortholog_one2one ) Dog_ STAT5B ( ortholog_one2one ) Macaque_ STAT5B ( ortholog_one2one ) Mouse_ Stat5b ( ortholog_one2one ) Pig_ STAT5B ( ortholog_one2one ) Rat_ Stat5b ( ortholog_one2one ) Rabbit_ STAT5B ( ortholog_one2one ) |
| Ohnologs | STAT1, STAT4, STAT6, STAT2 |
| Paralogs | STAT5A, STAT6, STAT2, STAT3, STAT4, STAT1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001578(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6MBW (X-ray 3.29A ) 6MBZ (X-ray 3.21A ) |
| DBSNP | rs2277619 rs1555549674 rs1555548680 rs1555548678 rs121908501 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:29844444}. Nucleus {ECO:0000269|PubMed:29844444}. Note=Translocated into the nucleus in response to phosphorylation. {ECO:0000269|PubMed:29844444}. |
| Mouse PG classification | NA |
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