Gene Information
Gene NameTFAP2C
OrganismHomo sapiens (Human)
Gene Length450
Protein NamesTranscription factor AP-2 gamma (AP2-gamma) (Activating enhancer-binding protein 2 gamma) (Transcription factor ERF-1)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000087510 )
Evolutionary StageEumetazoa
AlphaFoldDBQ92754
Gene CardTFAP2C
Uniprot IDQ92754
PfamPF03299
In ASDno
Allosteric Predictionno (-0.622870379)
Ortholog in AnimalsAlpaca_ TFAP2C ( ortholog_one2many )
Dog_ TFAP2C ( ortholog_one2one )
GuineaPig_ TFAP2C ( ortholog_one2one )
Macaque_ TFAP2C ( ortholog_one2one )
Mouse_ Tfap2c ( ortholog_one2one )
Pig_ TFAP2C ( ortholog_one2one )
Rat_ Tfap2c ( ortholog_one2one )
Rabbit_ TFAP2C ( ortholog_one2one )
OhnologsTFAP2B, TFAP2D, TFAP2E, TFAP2A
ParalogsTFAP2A, TFAP2B, TFAP2E, TFAP2D
Tissueskin, endocervix, esophagus.mucosa, lower.leg.skin, minor.salivary.gland, suprapubic.skin, vagina
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:24413532}.
Mouse PG classificationNA
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