Gene Information
Gene NameSPINK1
OrganismHomo sapiens (Human)
Gene Length79
Protein NamesSerine protease inhibitor Kazal-type 1 (Pancreatic secretory trypsin inhibitor) (Tumor-associated trypsin inhibitor) (TATI)
Target NameNA
Target TypeNA
Gene Age55 ( ENSG00000164266 )
Evolutionary StageMammalia
AlphaFoldDBP00995
Gene CardSPINK1
Uniprot IDP00995
PfamPF00050
In ASDno
Allosteric Predictionno (-0.537366687)
Ortholog in AnimalsAlpaca_ SPINK1 ( ortholog_one2one )
Dog_ SPINK1 ( ortholog_one2one )
GuineaPig_ SPINK1 ( ortholog_one2one )
Macaque_ SPINK1 ( ortholog_one2one )
Mouse_ Spink1 ( ortholog_one2one )
Pig_ SPINK1 ( ortholog_one2one )
Rat_ Spink1 ( ortholog_one2one )
Rabbit_ SPINK1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuepancreas
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1CGI  (X-ray  2.30A  1CGJ  (X-ray  2.30A  1HPT  (X-ray  2.30A  7QE8  (X-ray  2.90A  7QE9  (X-ray  2.10A 
DBSNP rs35877720  rs104893939  rs17107315  rs111966833  rs35523678 
Subcellular location [CC]Secreted {ECO:0000269|PubMed:7142173}.
Mouse PG classificationHPG
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