Gene Information
Gene NameSERF1A
OrganismHomo sapiens (Human)
Gene Length110
Protein NamesSmall EDRK-rich factor 1 (Protein 4F5) (h4F5) (SMA modifier 1)
Target NameNA
Target TypeNA
Gene Age382 ( ENSG00000172058 )
3 ( ENSG00000275581 )
Evolutionary StageEukaryota
AlphaFoldDBO75920
Gene CardSERF1A;SERF1B
Uniprot IDO75920
PfamPF04419
In ASDno
Allosteric Predictionno (-0.997685422)
Ortholog in AnimalsDog_ SERF1A ( ortholog_one2many )
Mouse_ Serf1 ( ortholog_one2many )
Rat_ Serf1 ( ortholog_one2many )
OhnologsNA
ParalogsSERF1B
TissueNA
Tissue SpecificityIsoform Long is predominantly expressed in heart, brain and skeletal muscle. Isoform Short and Isoform Long are expressed throughout the central nervous system, including spinal cord. {ECO:0000269|PubMed:9731538}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:31034892}. Nucleus {ECO:0000269|PubMed:31034892}.
Mouse PG classificationNA
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