| Gene Information | |
|---|---|
| Gene Name | STAC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 364 |
| Protein Names | SH3 and cysteine-rich domain-containing protein 3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000185482 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96MF2 |
| Gene Card | STAC3 |
| Uniprot ID | Q96MF2 |
| Pfam | PF00130; PF00018; PF07653 |
| In ASD | no |
| Allosteric Prediction | no (-0.17815664) |
| Ortholog in Animals | Alpaca_ STAC3 ( ortholog_one2one ) GuineaPig_ STAC3 ( ortholog_one2one ) Macaque_ STAC3 ( ortholog_one2one ) Mouse_ Stac3 ( ortholog_one2one ) Rat_ Stac3 ( ortholog_one2one ) Rabbit_ STAC3 ( ortholog_one2one ) |
| Ohnologs | STAC2, STAC |
| Paralogs | STAC2, STAC |
| Tissue | skeletal.muscle, artery, tongue |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DB6 (NMR - ) 6B29 (X-ray 1.30A ) 6UY7 (X-ray 2.10A ) 6UY8 (X-ray 1.65A ) 6UY9 (X-ray 1.60A ) |
| DBSNP | rs140291094 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q8BZ71}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q8BZ71}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8BZ71}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8BZ71}. Cell membrane, sarcolemma, T-tubule {ECO:0000250|UniProtKB:Q8BZ71}. Note=Co-localizes with CACNA1S and CACNA1C on T-tubules. {ECO:0000250|UniProtKB:Q8BZ71}. |
| Mouse PG classification | NA |
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