| Gene Information | |
|---|---|
| Gene Name | STA |
| Organism | Homo sapiens (Human) |
| Gene Length | 254 |
| Protein Names | Emerin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P50402 |
| Gene Card | EMD |
| Uniprot ID | P50402 |
| Pfam | PF03020 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Skeletal muscle, heart, colon, testis, ovary and pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JEI (NMR - ) 2ODC (NMR - ) 2ODG (NMR - ) 6GHD (X-ray 2.10A ) 6RPR (X-ray 2.26A ) 7NDY (X-ray 1.44A ) |
| DBSNP | rs2070818 rs104894805 rs104894806 |
| Subcellular location [CC] | Nucleus inner membrane {ECO:0000269|PubMed:19167377}; Single-pass membrane protein; Nucleoplasmic side {ECO:0000269|PubMed:19167377}. Nucleus outer membrane. Note=Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle-attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus. |
| Mouse PG classification | NA |
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