| Gene Information | |
|---|---|
| Gene Name | ST8SIA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8-sialyltransferase III) (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3) (Sialyltransferase 8C) (SIAT8-C) (Sialyltransferase St8Sia III) (ST8SiaIII) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000177511 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43173 |
| Gene Card | ST8SIA3 |
| Uniprot ID | O43173 |
| Pfam | PF00777 |
| In ASD | no |
| Allosteric Prediction | no (-0.625187152) |
| Ortholog in Animals | Alpaca_ ST8SIA3 ( ortholog_one2one ) Dog_ ST8SIA3 ( ortholog_one2one ) GuineaPig_ ST8SIA3 ( ortholog_one2one ) Macaque_ ST8SIA3 ( ortholog_one2one ) Mouse_ St8sia3 ( ortholog_one2one ) Pig_ ST8SIA3 ( ortholog_one2one ) Rat_ St8sia3 ( ortholog_one2one ) Rabbit_ ST8SIA3 ( ortholog_one2one ) |
| Ohnologs | ST8SIA2 |
| Paralogs | ST8SIA2, ST8SIA4, ST8SIA5, ST8SIA6, ST8SIA1 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in fetal and adult brain and fetal liver. {ECO:0000269|PubMed:9826427}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5BO6 (X-ray 2.07A ) 5BO7 (X-ray 1.85A ) 5BO8 (X-ray 2.70A ) 5BO9 (X-ray 2.30A ) 5CXY (X-ray 2.15A ) |
| DBSNP | rs3745060 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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