| Gene Information | |
|---|---|
| Gene Name | OTULIN |
| Organism | Homo sapiens (Human) |
| Gene Length | 352 |
| Protein Names | Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000154124 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96BN8 |
| Gene Card | OTULIN |
| Uniprot ID | Q96BN8 |
| Pfam | PF16218 |
| In ASD | no |
| Allosteric Prediction | no (-0.998423736) |
| Ortholog in Animals | Alpaca_ OTULIN ( ortholog_one2one ) Dog_ OTULIN ( ortholog_one2one ) GuineaPig_ OTULIN ( ortholog_one2one ) Macaque_ OTULIN ( ortholog_one2one ) Mouse_ Otulin ( ortholog_one2one ) Pig_ OTULIN ( ortholog_one2one ) Rat_ Otulin ( ortholog_one2one ) Rabbit_ OTULIN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | OTULINL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002323(Rat);0.030769(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ZNV (X-ray 1.30A ) 3ZNX (X-ray 1.35A ) 3ZNZ (X-ray 1.90A ) 4KSJ (X-ray 1.60A ) 4KSK (X-ray 2.40A ) 4KSL (X-ray 2.83A ) 4OYK (X-ray 2.00A ) 4P0B (X-ray 2.70A ) 5OE7 (X-ray 2.95A ) 6I9C (X-ray 1.77A ) 6SAK (X-ray 2.00A ) |
| DBSNP | rs11953822 rs9312870 rs886037887 rs886037885 rs9312870 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23746843}. |
| Mouse PG classification | NA |
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