| Gene Information | |
|---|---|
| Gene Name | TMEM53 |
| Organism | Homo sapiens (Human) |
| Gene Length | 277 |
| Protein Names | Transmembrane protein 53 (Nuclear envelope transmembrane protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000126106 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6P2H8 |
| Gene Card | TMEM53 |
| Uniprot ID | Q6P2H8 |
| Pfam | PF05705 |
| In ASD | no |
| Allosteric Prediction | no (-1.614349006) |
| Ortholog in Animals | Alpaca_ TMEM53 ( ortholog_one2one ) Dog_ TMEM53 ( ortholog_one2one ) GuineaPig_ TMEM53 ( ortholog_one2one ) Macaque_ TMEM53 ( ortholog_one2one ) Mouse_ Tmem53 ( ortholog_one2one ) Pig_ TMEM53 ( ortholog_one2one ) Rat_ Tmem53 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Widely expressed. {ECO:0000269|PubMed:33824347}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus outer membrane {ECO:0000269|PubMed:33824347}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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