| Gene Information | |
|---|---|
| Gene Name | ST6GAL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 529 |
| Protein Names | Beta-galactoside alpha-2,6-sialyltransferase 2 (Alpha 2,6-ST 2) (EC 2.4.3.1) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2) (ST6Gal II) (ST6GalII) (hST6Gal II) (Sialyltransferase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000144057 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96JF0 |
| Gene Card | ST6GAL2 |
| Uniprot ID | Q96JF0 |
| Pfam | PF00777 |
| In ASD | no |
| Allosteric Prediction | no (-0.785646746) |
| Ortholog in Animals | Alpaca_ ST6GAL2 ( ortholog_one2one ) GuineaPig_ ST6GAL2 ( ortholog_one2one ) Macaque_ ST6GAL2 ( ortholog_one2one ) Mouse_ St6gal2 ( ortholog_one2one ) Pig_ ST6GAL2 ( ortholog_one2one ) Rat_ St6gal2 ( ortholog_one2one ) Rabbit_ ST6GAL2 ( ortholog_one2one ) |
| Ohnologs | ST6GAL1 |
| Paralogs | ST6GALNAC5, C20orf173, ST3GAL4, ST3GAL3, ST3GAL2, ST6GAL1, ST6GALNAC4, ST6GALNAC3, ST6GALNAC6, ST6GALNAC2, ST3GAL5, ST3GAL6, ST6GALNAC1, ST3GAL1 |
| Tissue | brain, thyroid, cerebral.cortex, aorta, coronary.artery |
| Tissue Specificity | Weakly expressed in some tissues, such as small intestine, colon and fetal brain. {ECO:0000269|PubMed:12235148, ECO:0000269|PubMed:12603328}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs3796110 rs12615112 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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