| Gene Information | |
|---|---|
| Gene Name | ST3GAL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 333 |
| Protein Names | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (Alpha 2,3-ST 4) (Beta-galactoside alpha-2,3-sialyltransferase 4) (EC 2.4.3.2) (EC 2.4.3.4) (Alpha 2,3-sialyltransferase IV) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (Gal-beta-1,4-GlcNAc-alpha-2,3-sialyltransferase) (N-acetyllactosaminide alpha-2,3-sialyltransferase) (EC 2.4.3.6) (SAT-3) (ST-4) (ST3Gal IV) (ST3GalIV) (ST3GalA.2) (STZ) (Sialyltransferase 4C) (SIAT4-C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000110080 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q11206 |
| Gene Card | ST3GAL4 |
| Uniprot ID | Q11206 |
| Pfam | PF00777 |
| In ASD | no |
| Allosteric Prediction | no (-1.075813164) |
| Ortholog in Animals | Alpaca_ ST3GAL4 ( ortholog_one2one ) Dog_ ST3GAL4 ( ortholog_one2one ) GuineaPig_ ST3GAL4 ( ortholog_one2one ) Macaque_ ST3GAL4 ( ortholog_one2one ) Mouse_ St3gal4 ( ortholog_one2one ) Pig_ ST3GAL4 ( ortholog_one2one ) Rat_ St3gal4 ( ortholog_one2one ) Rabbit_ ST3GAL4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ST6GALNAC5, C20orf173, ST3GAL3, ST3GAL2, ST6GAL1, ST6GALNAC4, ST6GALNAC3, ST6GALNAC6, ST6GALNAC2, ST3GAL5, ST3GAL6, ST6GAL2, ST6GALNAC1, ST3GAL1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in adult placenta, heart and kidney. {ECO:0000269|PubMed:8288606}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. |
| Mouse PG classification | NA |
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