| Gene Information | |
|---|---|
| Gene Name | HSPD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 573 |
| Protein Names | 60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) |
| Target Name | mitochondrial matrix protein p1 |
| Target Type | Clinical trial target |
| Gene Age | >4290 ( ENSG00000144381 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P10809 |
| Gene Card | HSPD1 |
| Uniprot ID | P10809 |
| Pfam | PF00118 |
| In ASD | no |
| Allosteric Prediction | yes (0.568798063) |
| Ortholog in Animals | Alpaca_ HSPD1 ( ortholog_one2one ) GuineaPig_ HSPD1 ( ortholog_one2one ) Mouse_ Hspd1 ( ortholog_one2one ) Pig_ HSPD1 ( ortholog_one2one ) Rabbit_ HSPD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TCP1, BBS12, CCT2, CCT6A, CCT4, CCT6B, CCT7, CCT5, CCT8L2, CCT8, CCT3, PIKFYVE, MKKS |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.292178(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4PJ1 (X-ray 3.15A ) 6HT7 (X-ray 3.70A ) 6MRC (EM 3.08A ) 6MRD (EM 3.82A ) 7AZP (EM 3.50A ) 7L7S (EM 3.50A ) |
| DBSNP | rs72466451 rs66468541 |
| Subcellular location [CC] | Mitochondrion matrix. |
| Mouse PG classification | NA |
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