| Gene Information | |
|---|---|
| Gene Name | GSTZ1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 216 |
| Protein Names | Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18) |
| Target Name | maleylacetoacetate isomerase |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100577 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O43708 |
| Gene Card | GSTZ1 |
| Uniprot ID | O43708 |
| Pfam | PF14497; PF13417 |
| In ASD | no |
| Allosteric Prediction | no (-0.143139892) |
| Ortholog in Animals | Alpaca_ GSTZ1 ( ortholog_one2one ) Dog_ GSTZ1 ( ortholog_one2one ) GuineaPig_ GSTZ1 ( ortholog_one2one ) Macaque_ GSTZ1 ( ortholog_one2one ) Mouse_ Gstz1 ( ortholog_one2one ) Pig_ GSTZ1 ( ortholog_one2one ) Rat_ Gstz1 ( ortholog_one2one ) Rabbit_ GSTZ1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CLIC2, GSTO2, GDAP1L1, CLIC3, GSTT4, CLIC4, GSTT2, GSTT2B, CLIC1, EEF1G, GDAP1, GSTO1, CLIC6, CLIC5 |
| Tissue | NA |
| Tissue Specificity | Mostly expressed in liver followed by kidney, skeletal muscle and brain. Also expressed in melanocytes, synovium, placenta, breast and fetal liver and heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1FW1 (X-ray 1.90A ) |
| DBSNP | rs7975 rs7972 rs1046428 rs2234955 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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