| Gene Information | |
|---|---|
| Gene Name | SSTR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 418 |
| Protein Names | Somatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SST3) (SSR-28) |
| Target Name | somatostatin receptor type 3 |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000278195 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P32745 |
| Gene Card | SSTR3 |
| Uniprot ID | P32745 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.210707315) |
| Ortholog in Animals | Alpaca_ SSTR3 ( ortholog_one2one ) Dog_ SSTR3 ( ortholog_one2one ) GuineaPig_ SSTR3 ( ortholog_one2one ) Macaque_ SSTR3 ( ortholog_one2one ) Mouse_ Sstr3 ( ortholog_one2one ) Pig_ SSTR3 ( ortholog_one2one ) Rat_ Sstr3 ( ortholog_one2one ) Rabbit_ SSTR3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SSTR5, SSTR4, NPBWR1, OPRL1, GPR149, OPRM1, OPRK1, PTGDR2, CMKLR2, SSTR1, LTB4R, LTB4R2, KISS1R, UTS2R, NPBWR2, SSTR2, OPRD1 |
| Tissue | NA |
| Tissue Specificity | Brain, pituitary and pancreas. {ECO:0000269|PubMed:1337145}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4988466 rs34943557 rs6413537 rs4988469 rs229568 rs4988471 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation. {ECO:0000250}. |
| Mouse PG classification | NA |
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