| Gene Information | |
|---|---|
| Gene Name | CIT |
| Organism | Homo sapiens (Human) |
| Gene Length | 2027 |
| Protein Names | Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21) |
| Target Name | citron rho-interacting kinase |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122966 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14578 |
| Gene Card | CIT |
| Uniprot ID | O14578 |
| Pfam | PF00780; PF00169; PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.036108503) |
| Ortholog in Animals | Alpaca_ CIT ( ortholog_one2one ) Dog_ CIT ( ortholog_one2one ) GuineaPig_ CIT ( ortholog_one2one ) Macaque_ CIT ( ortholog_one2one ) Mouse_ Cit ( ortholog_one2one ) Pig_ CIT ( ortholog_one2one ) Rat_ Cit ( ortholog_one2one ) Rabbit_ CIT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ROCK1, ROCK2, CDC42BPA, CDC42BPG, CDC42BPB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.019355(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs36054900 rs56193743 rs886037892 rs886037893 rs886037894 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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