| Gene Information | |
|---|---|
| Gene Name | SSPN |
| Organism | Homo sapiens (Human) |
| Gene Length | 243 |
| Protein Names | Sarcospan (K-ras oncogene-associated protein) (Kirsten-ras-associated protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000123096 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14714 |
| Gene Card | SSPN |
| Uniprot ID | Q14714 |
| Pfam | PF04103 |
| In ASD | no |
| Allosteric Prediction | no (-0.690126658) |
| Ortholog in Animals | Alpaca_ SSPN ( ortholog_one2one ) Dog_ SSPN ( ortholog_one2one ) GuineaPig_ SSPN ( ortholog_one2one ) Macaque_ SSPN ( ortholog_one2one ) Mouse_ Sspn ( ortholog_one2one ) Pig_ SSPN ( ortholog_one2one ) Rat_ Sspn ( ortholog_one2one ) Rabbit_ SSPN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12313670 rs12313736 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000250}. Postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions. {ECO:0000250}. |
| Mouse PG classification | NA |
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