| Gene Information | |
|---|---|
| Gene Name | JPH3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 748 |
| Protein Names | Junctophilin-3 (JP-3) (Junctophilin type 3) (Trinucleotide repeat-containing gene 22 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000154118 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8WXH2 |
| Gene Card | JPH3 |
| Uniprot ID | Q8WXH2 |
| Pfam | PF02493 |
| In ASD | no |
| Allosteric Prediction | yes (0.570729738) |
| Ortholog in Animals | Alpaca_ JPH3 ( ortholog_one2one ) Dog_ JPH3 ( ortholog_one2one ) GuineaPig_ JPH3 ( ortholog_one2one ) Macaque_ JPH3 ( ortholog_one2one ) Mouse_ Jph3 ( ortholog_one2one ) Rat_ Jph3 ( ortholog_one2one ) |
| Ohnologs | JPH2, JPH4, JPH1 |
| Paralogs | JPH2, JPH1, JPH4 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Specifically expressed in brain. {ECO:0000269|PubMed:10891348}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17857118 rs17853660 rs17853661 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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