| Gene Information | |
|---|---|
| Gene Name | SSI2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 198 |
| Protein Names | Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O14508 |
| Gene Card | SOCS2 |
| Uniprot ID | O14508 |
| Pfam | PF00017; PF07525 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | High expression in heart, placenta, lung, kidney and prostate. Predominantly expressed in pulmonary epithelia cells, specifically type II pneumocytes. {ECO:0000269|PubMed:31578312, ECO:0000269|PubMed:9266833}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002808(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2C9W (X-ray 1.90A ) 4JGH (X-ray 3.00A ) 5BO4 (X-ray 2.90A ) 6I4X (X-ray 2.69A ) 6I5J (X-ray 2.80A ) 6I5N (X-ray 1.98A ) 7M6T (X-ray 3.19A ) |
| DBSNP | rs3741676 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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