| Gene Information | |
|---|---|
| Gene Name | PTPN21 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1174 |
| Protein Names | Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000070778 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q16825 |
| Gene Card | PTPN21 |
| Uniprot ID | Q16825 |
| Pfam | PF09380; PF00373; PF09379; PF00102 |
| In ASD | no |
| Allosteric Prediction | no (-0.0324664) |
| Ortholog in Animals | Alpaca_ PTPN21 ( ortholog_one2one ) Dog_ PTPN21 ( ortholog_one2one ) GuineaPig_ PTPN21 ( ortholog_one2one ) Macaque_ PTPN21 ( ortholog_one2one ) Mouse_ Ptpn21 ( ortholog_one2one ) Pig_ PTPN21 ( ortholog_one2one ) Rat_ Ptpn21 ( ortholog_one2one ) Rabbit_ PTPN21 ( ortholog_one2one ) |
| Ohnologs | PTPN14 |
| Paralogs | PTPN12, PTPRC, PTPN6, PTPN18, PTPN7, PTPN1, PTPN13, PTPRF, PTPRK, PTPRB, PTPRA, PTPN22, PTPRG, PTPRR, PTPN5, PTPN23, PTPRZ1, PTPN9, PTPRE, PTPN4, PTPRT, PTPRS, PTPRD, PTPN2, PTPRO, PTPRJ, PTPRM, PTPN11, PTPN20, PTPRU, PTPN14, PTPN3, PTPRN, PTPRN2, PTPRH |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.044400(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2401751 rs12879993 rs2274736 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |