| Gene Information | |
|---|---|
| Gene Name | GAP43 |
| Organism | Homo sapiens (Human) |
| Gene Length | 238 |
| Protein Names | Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Neural phosphoprotein B-50) (pp46) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000172020 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P17677 |
| Gene Card | GAP43 |
| Uniprot ID | P17677 |
| Pfam | PF00612; PF06614; PF10580 |
| In ASD | no |
| Allosteric Prediction | no (-0.402457182) |
| Ortholog in Animals | Alpaca_ GAP43 ( ortholog_one2one ) Dog_ GAP43 ( ortholog_one2one ) GuineaPig_ GAP43 ( ortholog_one2one ) Macaque_ GAP43 ( ortholog_one2one ) Mouse_ Gap43 ( ortholog_one2one ) Pig_ GAP43 ( ortholog_one2one ) Rat_ Gap43 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPA17, RIIAD1 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6291 rs11557762 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:14978216}; Peripheral membrane protein {ECO:0000269|PubMed:14978216}; Cytoplasmic side {ECO:0000269|PubMed:14978216}. Cell projection, growth cone membrane {ECO:0000269|PubMed:14978216}; Peripheral membrane protein {ECO:0000269|PubMed:14978216}; Cytoplasmic side {ECO:0000269|PubMed:14978216}. Synapse {ECO:0000269|PubMed:14978216}. Cell projection, filopodium membrane {ECO:0000269|PubMed:14978216}; Peripheral membrane protein {ECO:0000269|PubMed:14978216}. Perikaryon {ECO:0000250|UniProtKB:P07936}. Cell projection, dendrite {ECO:0000250|UniProtKB:P07936}. Cell projection, axon {ECO:0000250|UniProtKB:P07936}. Cytoplasm {ECO:0000250|UniProtKB:P07936}. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes. {ECO:0000269|PubMed:14978216}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |