| Gene Information | |
|---|---|
| Gene Name | MARVELD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 173 |
| Protein Names | MARVEL domain-containing protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000155254 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BSK0 |
| Gene Card | MARVELD1 |
| Uniprot ID | Q9BSK0 |
| Pfam | PF01284 |
| In ASD | no |
| Allosteric Prediction | no (-1.637107219) |
| Ortholog in Animals | Alpaca_ MARVELD1 ( ortholog_one2one ) Dog_ MARVELD1 ( ortholog_one2one ) GuineaPig_ MARVELD1 ( ortholog_one2one ) Macaque_ MARVELD1 ( ortholog_one2one ) Mouse_ Marveld1 ( ortholog_one2one ) Pig_ MARVELD1 ( ortholog_one2one ) Rabbit_ MARVELD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CMTM2, PLP2, MAL, CMTM3, PLLP, CMTM4, CMTM8, CMTM1, MAL2, CMTM7, CKLF, MALL, CMTM6, CMTM5 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in normal tissues. Down-regulated in multiple primary tumors. {ECO:0000269|PubMed:19364627}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000269|PubMed:19364627}. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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