| Gene Information | |
|---|---|
| Gene Name | MPP7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 576 |
| Protein Names | MAGUK p55 subfamily member 7 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000150054 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q5T2T1 |
| Gene Card | MPP7 |
| Uniprot ID | Q5T2T1 |
| Pfam | PF00625; PF02828; PF00595; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.634660869) |
| Ortholog in Animals | Alpaca_ MPP7 ( ortholog_one2one ) Dog_ MPP7 ( ortholog_one2one ) GuineaPig_ MPP7 ( ortholog_one2one ) Macaque_ MPP7 ( ortholog_one2one ) Mouse_ Mpp7 ( ortholog_one2one ) Pig_ MPP7 ( ortholog_one2one ) Rat_ Mpp7 ( ortholog_one2one ) Rabbit_ MPP7 ( ortholog_one2one ) |
| Ohnologs | MPP3, MPP4 |
| Paralogs | MPP3, MPP2, PALS1, CASK, PALS2, MPP1, MPP4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LRA (X-ray 2.95A ) 3O46 (X-ray 1.30A ) |
| DBSNP | rs2997211 |
| Subcellular location [CC] | Membrane; Peripheral membrane protein {ECO:0000269|PubMed:17332497}. Lateral cell membrane; Peripheral membrane protein {ECO:0000269|PubMed:17332497}. Cell junction, tight junction {ECO:0000269|PubMed:17237226, ECO:0000269|PubMed:17332497}. Cell junction, adherens junction {ECO:0000269|PubMed:17237226, ECO:0000269|PubMed:17332497}. Cytoplasm, cell cortex {ECO:0000269|PubMed:26481050}. Cytoplasm {ECO:0000269|PubMed:26481050}. Note=In epidermal cells, detected primarily at the lateral cell membrane. {ECO:0000269|PubMed:17332497}. |
| Mouse PG classification | NA |
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