| Gene Information | |
|---|---|
| Gene Name | NAP1L4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 375 |
| Protein Names | Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000205531 ) 3 ( ENSG00000273562 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q99733 |
| Gene Card | NAP1L4 |
| Uniprot ID | Q99733 |
| Pfam | PF00956 |
| In ASD | no |
| Allosteric Prediction | no (-0.631965185) |
| Ortholog in Animals | Alpaca_ NAP1L4 ( ortholog_one2one ) Dog_ NAP1L4 ( ortholog_one2one ) GuineaPig_ NAP1L4 ( ortholog_one2one ) Macaque_ NAP1L4 ( ortholog_one2one ) Mouse_ Nap1l4 ( ortholog_one2one ) Pig_ NAP1L4 ( ortholog_one2one ) Rat_ Nap1l4 ( ortholog_one2one ) Rabbit_ NAP1L4 ( ortholog_one2one ) |
| Ohnologs | NAP1L1 |
| Paralogs | TSPYL6, TSPY9, TSPY2, TSPY8, TSPY3, TSPY4, TSPY10, TSPY1, NAP1L3, TSPYL2, NAP1L2, SETSIP, NAP1L5, TSPYL5, TSPYL4, TSPYL1, SET, NAP1L1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Biallelically expressed in fetal and adult tissues. Highest levels in testis. {ECO:0000269|PubMed:8923002}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001740(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10764593, ECO:0000269|PubMed:9325046}. Cytoplasm {ECO:0000269|PubMed:10764593, ECO:0000269|PubMed:9325046}. Note=Present in the cytoplasm and excluded from the nucleus during G0/G1 phase, then relocates to the nucleus by the time cells are in S phase (PubMed:9325046). Phosphorylated form localizes in the cytoplasm during the G0/G1 transition, whereas dephosphorylation leads to relocalization into the nucleus at the G1/S-boundary (PubMed:10764593). {ECO:0000269|PubMed:10764593, ECO:0000269|PubMed:9325046}. |
| Mouse PG classification | NA |
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