| Gene Information | |
|---|---|
| Gene Name | BRIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1249 |
| Protein Names | Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000136492 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9BX63 |
| Gene Card | BRIP1 |
| Uniprot ID | Q9BX63 |
| Pfam | PF06733; PF13307 |
| In ASD | no |
| Allosteric Prediction | no (-0.507340447) |
| Ortholog in Animals | Alpaca_ BRIP1 ( ortholog_one2one ) Dog_ BRIP1 ( ortholog_one2one ) GuineaPig_ BRIP1 ( ortholog_one2one ) Macaque_ BRIP1 ( ortholog_one2one ) Mouse_ Brip1 ( ortholog_one2one ) Pig_ BRIP1 ( ortholog_one2one ) Rat_ Brip1 ( ortholog_one2one ) Rabbit_ BRIP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RTEL1, DDX11, ERCC2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed, with highest levels in testis. {ECO:0000269|PubMed:11301010}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.030769(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1T15 (X-ray 1.85A ) 1T29 (X-ray 2.30A ) 3AL3 (X-ray 2.15A ) |
| DBSNP | rs28903098 rs4988345 rs4988346 rs4988347 rs28997569 rs137852985 rs149364097 rs150624408 rs4988350 rs4988349 rs28997572 rs786202760 rs764803896 rs4988355 rs4986764 rs4988356 rs1199923024 rs28997573 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11301010, ECO:0000269|PubMed:23585563}. Cytoplasm {ECO:0000269|PubMed:23585563}. |
| Mouse PG classification | LPG |
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