| Gene Information | |
|---|---|
| Gene Name | GPX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 203 |
| Protein Names | Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) |
| Target Name | glutathione peroxidase 1 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000233276 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | GPX1 |
| Uniprot ID | P07203 |
| Pfam | PF00255 |
| In ASD | no |
| Allosteric Prediction | yes (0.236618062) |
| Ortholog in Animals | Alpaca_ GPX1 ( ortholog_one2one ) Dog_ GPX1 ( ortholog_one2one ) Macaque_ GPX1 ( ortholog_one2one ) Mouse_ Gpx1 ( ortholog_one2one ) Pig_ GPX1 ( ortholog_one2one ) Rat_ Gpx1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPX3, GPX4, GPX7, GPX8, GPX5, GPX2, GPX6 |
| Tissue | NA |
| Tissue Specificity | Expressed in platelets (at protein level). {ECO:0000269|PubMed:11115402}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2F8A (X-ray 1.50A ) |
| DBSNP | rs8179169 rs17838762 rs6446261 rs1050450 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | LPG |
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